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MediPoint: Trauma Fixation - EU Analysis and Market Forecasts

LONDON, Dec. 30, 2013 /PRNewswire/ -- Reportbuyer.com just published a new market research report:

MediPoint: Trauma Fixation - EU Analysis and Market Forecasts


MediPoint: Trauma Fixation - EU Analysis and Market Forecasts

Summary

Traumatic injury patients that come into the Emergency Room (ER) experience orthopedic injury in the form of fractures 60% to 65% of the time, based on GlobalData's conversations with key opinion leaders. Of this population, 45%–50% are operable and require fracture repair techniques in the form of external or internal fixation. As the global population continues to grow in the emerging markets, with overcrowding and economic growth, some of the drivers for trauma fixation include motor vehicle accidents and aging. GlobalData's analysis shows that while the orthopedics implant market is mature, where products have become commodities, trauma fixation is one that has room for more technological development and adoption.

The EU market is an unsure market with regards to high growth in trauma fixation. There is a strong dependence on reimbursement which can vary between nations. Moving forward GlobalData believes that the most growth will continue to be IM nails, due to the minimally invasive approach they have compared with other systems.

Scope

- An overview of bone trauma, which includes epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines.
- Annualized EU trauma fixation market revenue and future forecasts from 2009 to 2011, forecast for 7 years to 2018.
- Investigation of current and future market competition for trauma fixation
- Insightful review of the key industry drivers, restraints and challenges as well as predicted impact of key events.
- Competitor assessment including device approval analysis and device sales forecasts.
- Marketed and pipeline product profiles covering efficiency, safety, clinical study details, device approvals, product positioning and device sales forecast.
- Analysis of unmet needs within the market and opportunities for future players.
- Technology trends evaluation to assess strength of pipeline.
- An overview of all devices in development including clinical study details, design and material selection considerations, efficacy reports, and device approval timelines.
- Company profiles including business description, financial overview and SWOT analysis.
- Coverage of key market players.
- Strategic assessment of the trauma fixation sector through market impact analysis, future market scenario and company analysis.
- Direct quotes from Key Opinion Leaders (KOL) as well as Orthopedic Surgeons.

Reasons to buy

- Understand the trends shaping and driving the EU trauma fixation Market.
- Realize device preferences of physicians who have performed the tests already.
- Access market sizing, forecasts and quantified growth opportunities in the EU trauma fixation market through 2018.
- Quantify candidate patient populations to better design product pricing & launch plans.
- Drive revenues, formulate effective sales and marketing strategies and gain in-depth understanding of the competitive landscape.
- Perform benchmarking analysis of growth opportunities against currently marketed products.
- Assess competitiveness of products in market by understanding the strengths and weaknesses of current competition.
- Take a comprehensive look at the market's device pipeline and identify promising, paradigm-shifting products.
- Create an effective counter-strategy to gain a competitive advantage against those currently in the market.
- Organize your sales and marketing efforts by identifying the market categories and segments that present the best opportunities for growth.
- What's the next big thing in EU trauma fixation market landscape? Identify, understand and capitalize.

Table of Contents

Table of Contents 9
1.1 List of Tables 15
1.2 List of Figures 19
2 Introduction 21
2.1 Catalyst 22
3 Disease Overview 24
3.1 Anatomy and Physiology 24
3.1.1 Bone Biology 24
3.1.2 Skeletal Structure 24
3.2 Pathophysiology 27
3.2.1 Overview 27
3.2.2 Post-Traumatic Arthritis 27
3.2.3 Fracture 27
3.3 Clinical Presentation 28
3.3.1 Symptoms 28
3.3.2 Fracture Types 29
3.3.3 Fractures by Location 31
3.3.4 Hip Injury 33
3.4 Clinical Outcomes 34
3.4.1 Immobilization 34
3.4.2 Plates and Screws 35
3.4.3 Intramedullary Nails 37
3.4.4 Hip Fixation Device Options 38

3.4.5 External Fixation 40
4 Industry Overview 41
4.1 Overview 41
4.2 Procedure Trends 43
4.2.1 EU 43
4.3 Market Access 44
4.3.1 EU 44
4.4 Regulatory Issues / Recalls 51
4.4.1 Rigid FX FDA Warning Letter 51
4.4.2 DePuy Orthopedics LBS Lower Extremity Dovetail Intercalary Component Recall 51
4.5 Mergers, Acquisitions and Partnerships 52
4.5.1 Zimmer Acquires NORMED Medizin-Technik 52
4.5.2 Smith & Nephew Acquires Adler Mediequip Private Limited 52
4.5.3 Smith & Nephew plc Announces Acquisition of Brazil Distribution Business 52
4.5.4 Biomet Inc. Acquires DePuy Trauma 52
4.5.5 Zimmer Acquires ExtraOrtho XtraFix External Fixation Product Line 53
4.5.6 DePuy Orthopaedics (Johnson & Johnson) and Synthes Inc. Merge 53
4.5.7 Synthes Inc. and AO Foundation Partnership 53
4.6 Economic Impact 54
4.6.1 Developed Countries 54
4.6.2 Emerging Markets 55
4.7 Market Drivers 55
4.7.1 Rising Prevalence 55
4.7.2 Development Due to War 58
4.7.3 Bone Regeneration 59
4.7.4 Commoditization of Orthopedic Market 60
4.7.5 Patient Demand and Awareness 60
4.7.6 Technological Developments 61

4.7.7 Rising Competition and Innovation through Small Players 62
4.7.8 Materials Development 63
4.8 Market Opportunities 65
4.8.1 Mergers and Acquisitions 65
4.8.2 Emerging Markets 65
4.8.3 Extremities Growth 66
4.8.4 Capitalizing on Market Fragmentation 67
4.9 Market Barriers 68
4.9.1 Burden of Rising Regulation 68
4.9.2 Proving Efficacy 69
4.9.3 Pricing Pressures and Reimbursement 70
4.9.4 Medical Device Excise Tax 71
4.10 Substitutes 71
4.10.1 Joint Replacement 71
4.10.2 Generic Implants 72
4.10.3 External Fixation 73
5 Competitive Assessment 74
5.1 Overview 74
5.2 Global Market Share 74
5.2.1 Global Market Share 74

5.2.2 EU Market Share 77
5.3 Marketed Products 83
5.3.1 Key Internal Fixation Products 84
5.3.2 Key External Fixation Devices 118
6 Unmet Needs 122
6.1 Addressing the Complications 122
6.2 Advanced Materials Research 123
6.3 Improving Borderline Patient Treatment Outcomes 124
6.4 Bioabsorbable Technology Development 124
6.5 Centralization 125
6.6 Cost Containment 125
6.7 Drug-Eluting Implants 126
6.8 Long-Term Clinical Data 127
6.9 Trauma Registry 128
7 Pipeline Products 130
7.1 Overview 130
7.2 Product Profiles 130
7.2.1 Drug-Releasing Screws by Bioretec 130
7.2.2 Small Bone Innovations Arthrodesis Plates 130
7.2.3 Semprus Biosciences Trauma Fixation Devices 130
7.2.4 Nanova Inc. Bioabsorbable Bone Screws 130
7.2.5 CAMBfix Ltd. Pipeline 131
7.2.6 Nutek Orthopaedics LLC External Fixation Pipeline 131
7.2.7 Innovia LLC Develops IM Nail 131
8 Clinical Trials to Watch 132
8.1 Overview 132
8.2 Orthopedic Trauma Patient Quality of Life Trial 132
8.3 Non-Operative vs. Operative Management of Olecranon Fractures 133
8.4 Smith & Nephew INTUIT Hip Fracture Study 133
8.5 Distal Radius Fracture Fixation Comparison 134
8.6 Nails versus Plates for Femur Fractures in Dar es Salaam, Tanzania 134
9 Current and Future Players 135
9.1 Trends in Corporate Strategy 135
9.2 Company Profiles 136
9.2.1 Acumed 136

9.2.2 Biomet 138
9.2.3 DePuy Synthes International 140
9.2.4 Integra LifeSciences 142
9.2.5 Orthofix 144
9.2.6 OsteoMed 146
9.2.7 Small Bone Innovations, Inc. 147
9.2.8 Smith & Nephew 149
9.2.9 Stryker 151
9.2.10 Tornier 153
9.2.11 Trimed Inc. 156
9.2.12 Wright Medical 157
9.2.13 Zimmer 159
9.2.14 Companies in Trauma 162
10 Market Outlook 166
10.1 EU 166
10.1.1 Overview 166
10.1.2 France 168
10.1.3 Germany 170
10.1.4 Italy 172
10.1.5 Spain 173
10.1.6 UK 175
11 Appendix 177
11.1 Abbreviations 177
11.2 Bibliography 179
11.3 Research Methodology 189
11.3.1 Overview 189
11.3.2 Coverage 189
11.3.3 Secondary Research 190
11.3.4 Forecasting Methodology 190
11.3.5 Primary Research – Key Opinion Leader Interviews 192
11.3.6 Primary Research – Physician Survey 192
11.3.7 Expert Panel Validation 194
11.4 Physicians and Specialists Included in this Study 194
11.4.1 Dr. Philippe Bellemère 194
11.4.2 Julio Duarte Clemente, MD, PhD. 194

11.4.3 Dr. Moussa Hamadouche 194
11.4.4 Dr. Vidhya Ravi 194
11.4.5 Robert M. Szabo, MD, MPH 194
11.4.6 Dr. Marcello Zaia Oliveira 195
11.4.7 Robert Zura, MD 195
11.5 About the Authors 195
11.5.1 Analysts 195
11.5.2 Global Head of Healthcare 196
11.6 About MediPoint 197
11.7 About GlobalData 197
11.8 Disclaimer 197

List of Tables

Table 1: Clinical Symptoms and Descriptions 28
Table 2: Fracture Locations in the Body 32
Table 3: Locking Plates vs. Non-Locking Plates Features 35
Table 4: IM Nail Technical Specifications 37
Table 5: Fixation Types for Hip Fractures 38
Table 6: Regulatory Differences Between the US and EU 44
Table 7: Direct and Indirect Costs of Orthopedics 54
Table 8: Acumed Lower Extremity Internal Fixation Products and Screws 84
Table 9: Acumed Upper Extremity Internal Fixation Products 85
Table 10: Acumed Plate and Screw Systems SWOT 86
Table 11: Acumed IM Nail Systems SWOT 86
Table 12: Biomet Internal Fixation Plates and Screws 87
Table 13: Biomet Internal Fixation IM Nails 88

Table 14: Biomet Plate and Screw Systems SWOT 88
Table 15: Biomet IM Nail Systems SWOT 89
Table 16: Bioretec Internal Fixation Implants 90
Table 17: Bioretec Bioabsorbable Screws SWOT 90
Table 18: DePuy Synthes Plates and Screws 92
Table 19: DePuy Synthes Intramedullary Nails 93
Table 20: DePuy Synthes Plate and Screw Systems SWOT 93
Table 21: DePuy Synthes IM Nail Systems SWOT 94
Table 22: Extremity Medical Plates, Screws and Nails 94
Table 23: Extremity Medical Internal Fixation Systems SWOT 95
Table 24: Integra Life Sciences Lower Extremity Internal Fixation Products 96
Table 25: Integra Life Sciences Upper Extremity Internal Fixation Products 97
Table 26: Integra Life Sciences Internal Fixation Systems SWOT 98
Table 27: Orthofix Internal Fixation Plates and Screws 98
Table 28: Orthofix Internal Fixation IM Nails 99
Table 29: Orthofix Plate and Screw Systems SWOT 99
Table 30: Orthofix IM Nails SWOT 99
Table 31: Osteomed Internal Fixation Lower Extremity 100
Table 32: Osteomed Internal Fixation Upper Extremity 100
Table 33: Osteomed Upper Extremity Systems SWOT 101
Table 34: Osteomed Lower Extremity Systems SWOT 101
Table 35: Small Bone Innovations Internal Fixation Lower Extremity 102

Table 36: Small Bone Innovations Internal Fixation Upper Extremity 103
Table 37: SBi Upper Extremity Systems SWOT 104
Table 38: SBi Lower Extremity Systems SWOT 104
Table 39: Smith & Nephew Internal Fixation 105
Table 40: Smith & Nephew Plate and Screw Systems SWOT 105
Table 41: Stryker Internal Fixation Upper Extremity 106
Table 42: Stryker Internal Fixation Lower Extremity 107
Table 43: Stryker Internal Fixation Foot and Ankle 108
Table 44: Stryker Upper Extremity Systems SWOT 108
Table 45: Stryker Lower Extremity Systems SWOT 109
Table 46: Tornier Internal Fixation Upper Extremity 110
Table 47: Tornier Plate and Screw Systems SWOT 111
Table 48: Trimed Internal Fixation Lower Extremity 112
Table 49: Trimed Internal Fixation Upper Extremity 113
Table 50: Trimed Plate and Screw Systems SWOT 113
Table 51: Wright Medical Internal Fixation Lower Extremity Plates and Screws 114
Table 52: Wright Medical Internal Fixation Upper Extremity Plates and Screws 115
Table 53: Wright Medical Lower Extremity Plate and Screw Systems SWOT 116
Table 54: Wright Medical Upper Extremity Plate and Screw Systems SWOT 116
Table 55: Zimmer Internal Fixation Plates and Screws 117

Table 56: Zimmer Internal Fixation IM Nails 117
Table 57: Zimmer Plate and Screw Systems SWOT 117
Table 58: Zimmer IM Nail System SWOT 118
Table 59: Biomet External Fixation 118
Table 60: DePuy Synthes External Fixation 118
Table 61: Orthofix External Fixation 119
Table 62: Smith & Nephew External Fixation 120
Table 63: Stryker External Fixation 120
Table 64: Wright Medical External Fixation 121
Table 65: Zimmer External Fixation 121
Table 66: Orthopedic Trauma Patient Quality of Life Trial 132
Table 67: Non-Operative vs. Operative Management of Olecranon Fractures 133
Table 68: INTUIT Hip Fracture Outcome Study 133
Table 69: Distal Radius Fracture Fixation Comparison 134
Table 70: Nails versus Plates for Femur Fractures in Dar es Salaam, Tanzania 134
Table 71: Company Profile – Acumed LLC 136
Table 72: SWOT Analysis – Acumed LLC 137
Table 73: Company Profile – Biomet Orthopedics 138
Table 74: SWOT Analysis – Biomet Orthopedics 139
Table 75: Company Profile – DePuy Synthes International 141
Table 76: SWOT Analysis – DePuy Synthes International 142
Table 77: Company Profile – Integra LifeSciences Inc. 143
Table 78: SWOT Analysis – Integra LifeSciences Inc. 144
Table 79: Company Profile – Orthofix Inc. 145
Table 80: SWOT Analysis – Orthofix Inc. 145
Table 81: Company Profile – OsteoMed 146
Table 82: SWOT Analysis – OsteoMed 147
Table 83: Company Profile – Small Bone Innovations Inc. 148
Table 84: SWOT Analysis – Small Bone Innovations Inc. 148
Table 85: Company Profile – Smith & Nephew 149

Table 86: SWOT Analysis – Smith & Nephew 150
Table 87: Company Profile – Stryker 152
Table 88: SWOT Analysis – Stryker 153
Table 89: Company Profile – Tornier N.V. 154
Table 90: SWOT Analysis – Tornier N.V. 155
Table 91: Company Profile – Trimed, Inc. 156
Table 92: SWOT Analysis – Trimed 157
Table 93: Company Profile – Wright Medical 158
Table 94: SWOT Analysis – Wright Medical 159
Table 95: Company Profile – Zimmer Holdings Inc. 160
Table 96: SWOT Analysis – Zimmer Holdings, Inc. 161
Table 97: Trauma Companies in the Global Market 162
Table 98: Trauma Companies in APAC Market 164
Table 99: Trauma Fixation Sales ($m) Forecast for the EU, 2010–2019 167
Table 100: Trauma Fixation Sales ($m) Forecast for France, 2010–2019 169
Table 101: Trauma Fixation Sales ($m) Forecast for Germany, 2010–2019 171
Table 102: Trauma Fixation Sales ($m) Forecast for Italy, 2010–2019 172
Table 103: Trauma Fixation Sales ($m) Forecast for Spain, 2010–2019 174
Table 104: Trauma Fixation Sales ($m) Forecast for the UK, 2010–2019 175

1.2 List of Figures
Figure 1: Skeletal Structure 25
Figure 2: Joint Structure 26
Figure 3: Fracture Types 29
Figure 4: Hip Fracture Types 33
Figure 5: Hip Fracture Distribution 38
Figure 6: Fracture by Bones, 2008 41

Figure 7: Global Product Sales Volume for Trauma Fixation, 2010–2019 42
Figure 8: EU Product Sales Volume for Trauma Fixation, 2010–2019 43
Figure 9: EU Adoption of Locking vs. Non-Locking Plates, 2010–2015 46
Figure 10: EU Adoption of Nails vs. Plate Systems vs. External Fixation, 2010–2015 46
Figure 11: Sources of Orthopedic Trauma (%) 56
Figure 12: Global Market Share for Plates and Screw Systems, 2012 75
Figure 13: Global Market Share for IM Nails, 2012 76
Figure 14: Global IM Nails Breakdown, 2012 76
Figure 15: Global Market Share for External Fixation, 2012 77
Figure 16: UK Market Share for Trauma Fixation, 2012 78
Figure 17: France Market Share for Trauma Fixation, 2012 78
Figure 18: Germany Market Share for Trauma Fixation, 2012 79
Figure 19: Italy Market Share for Trauma Fixation, 2012 79
Figure 20: Spain Market Share for Trauma Fixation, 2012 80
Figure 21: EU Market Share for Plates and Screw Systems, 2012 81
Figure 22: EU Market Share for IM Nails, 2012 82
Figure 23: EU Market Share for External Fixation Systems, 2012 82
Figure 24: Influencing Factors for Plate and Screw Products 83
Figure 25: Challenging Aspects in Trauma Surgery 127
Figure 26: EU Sales ($m) Forecast for Trauma Fixation, 2010–2019 167
Figure 27: France Sales ($m) Forecast for Trauma Fixation, 2010–2019 169
Figure 28: Germany Sales ($m) Forecast for Trauma Fixation, 2010–2019 171
Figure 29: Italy Sales ($m) Forecast for Trauma Fixation, 2010–2019 173
Figure 30: Spain Sales ($m) Forecast for Trauma Fixation, 2010–2019 174
Figure 31: UK Sales ($m) Forecast for Trauma Fixation, 2010–2019 176
Figure 32: Surgeon Location Breakdown Trauma Survey (n=103) 193
Figure 33: Surgeon Practice Setting Trauma Survey (n=103) 193

Companies Mentioned

Acumed
Biomet
DePuy Synthes International
Integra LifeSciences
Orthofix
OsteoMed
Small Bone Innovations, Inc.
Smith & Nephew
Stryker
Tornier
Trimed Inc.
Wright Medical
Zimmer

Read the full report:
MediPoint: Trauma Fixation - EU Analysis and Market Forecasts
http://www.reportbuyer.com/pharma_healthcare/treatments/orthopaedic/medipoint_trauma_fixation_eu_analysis_market_forecasts.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Orthopedic

For more information:
Sarah Smith
Research Advisor at Reportbuyer.com
Email: [email protected]
Tel: +44 208 816 85 48
Website: www.reportbuyer.com

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