|By PR Newswire||
|March 10, 2014 03:26 PM EDT||
BALTIMORE, Md., March 10, 2014 /PRNewswire-USNewswire/ -- With the opening of the 14th Annual Robert Packard Center for ALS Research Symposium, the Packard Center and The ALS Association are pleased to announce the first scientific grant award from the Winokur Family Research Initiative. The inaugural grant will help to fund a project under the direction on Phil Wong, Ph.D., a Professor of Pathology at Johns Hopkins University and Liam Chen, M.D., Ph.D., Assistant Professor of Pathology at Johns Hopkins University. The study will focus on the use of animal models of TDP-43-linked ALS-FTD (frontotemporal dementia) to validate and characterize newly identified therapeutic targets for ALS.
ALS (amyotrophic lateral sclerosis), otherwise known as Lou Gehrig's Disease, is a progressive neurodegenerative disease that affects neurons (nerve cells) in the brain and the spinal cord. Eventually, people with ALS lose the ability to initiate and control muscle movement, which often leads to total paralysis and death within two to five years of diagnosis. There is no cure and no life-prolonging treatments for the disease.
This study is important because it will help identify the valid targets needed for developing effective therapies for ALS. The targets identified by Drs. Wong and Chen will yield a clear understanding of how TDP-43 kills neurons that will identify and develop mechanism-based therapeutics. Previous studies have shown that TPD-43 proteinopathy, which involves malformed proteins, is common in both sporadic and familial ALS and FTD.
"The Packard Center is pleased to have the opportunity to, once again, partner with The ALS Association to work on this important project. We thank our friend Diane Winokur for her support of the work we do to combat ALS and are pleased to honor her and this initiative at the onset of our Annual Scientific Symposium," said Piera Pasinelli, Ph.D., the Packard Center's Science Director.
The Winokur Family Research Initiative was conceived and initiated specifically to fund promising early-stage research by The Association's Golden West Chapter. Through a unique collaboration between the Packard Center and The ALS Association, groundbreaking, targeted studies are supported by a peer-reviewed process that is results-oriented and highly accountable. The goal is to fund promising early-stage ALS research and move it forward more quickly. Besides providing needed funding for the organizations' ongoing commitment to ALS research, the Winokur Family Research Initiative will also encourage scientists to work together toward the ultimate goal of one day finding a treatment or cure for ALS.
Diane Winokur, founder of the Winokur Family Research Initiative, is a highly-respected leader in the fight against ALS. She, and her late husband, Bob, had first-hand knowledge of how devastating ALS is, having lost two sons, Douglas and Hugh, to the disease. Winokur serves on the boards of the Golden West Chapter and The Robert Packard Center for ALS Research and was recently appointed as the ALS and MS representative on the Independent Citizen's Oversight Committee, the governing body of the California Institute for Regenerative Medicine (CIRM).
"The ALS Association is delighted to honor Diane Winokur and partner with The Packard Center for ALS Research on this exciting project," said Lucie Bruijn, Ph.D. MBA, Chief Scientist of The ALS Association.
The Packard Center's Research Symposium is an annual meeting, held in Baltimore, Md., that brings together 145 clinicians and bench researchers, postdoctoral students, and advisory board members – all leaders in the field of ALS. This invitation-only event requires Packard-funded researchers to present their research findings that are subject to peer-reviews by the Center's Board of Scientific Advisors. The Symposium is a review of all research projects funded by the Packard Center, plus a series of updates from clinical partners at the Northeast ALS Consortium (NEALS). Attendees come from institutions in 21 states across the U.S., as well as from Canada, Belgium, Germany, France, Switzerland, and the United Kingdom.
About the Robert Packard Center for ALS Research
The Robert Packard Center for ALS Research at Johns Hopkins is the only international scientific operation dedicated solely to curing the disease. We are unique in our approach to fighting ALS, a motor neuron disease also known as Lou Gehrig's Disease, in that we combine and facilitate scientific collaboration and ALS research with fundraising for the development of new treatments and to finding a cure. For more information about the Center, visit http://www.alscenter.org/.
About The ALS Association
The ALS Association is the only national non-profit organization fighting Lou Gehrig's Disease on every front. By leading the way in global research, providing assistance for people with ALS through a nationwide network of chapters, coordinating multidisciplinary care through certified clinical care centers, and fostering government partnerships, The Association builds hope and enhances quality of life while aggressively searching for new treatments and a cure. For more information about The ALS Association, visit our website at www.alsa.org.
SOURCE The ALS Association
The 4th International DevOps Summit, co-located with16th International Cloud Expo – being held June 9-11, 2015, at the Javits Center in New York City, NY – announces that its Call for Papers is now open. Born out of proven success in agile development, cloud computing, and process automation, DevOps is a macro trend you cannot afford to miss. From showcase success stories from early adopters and web-scale businesses, DevOps is expanding to organizations of all sizes, including the world's large...
Nov. 27, 2014 09:45 AM EST Reads: 1,559
When an enterprise builds a hybrid IaaS cloud connecting its data center to one or more public clouds, security is often a major topic along with the other challenges involved. Security is closely intertwined with the networking choices made for the hybrid cloud. Traditional networking approaches for building a hybrid cloud try to kludge together the enterprise infrastructure with the public cloud. Consequently this approach requires risky, deep "surgery" including changes to firewalls, subnets...
Nov. 27, 2014 09:45 AM EST Reads: 829
Want to enable self-service provisioning of application environments in minutes that mirror production? Can you automatically provide rich data with code-level detail back to the developers when issues occur in production? In his session at DevOps Summit, David Tesar, Microsoft Technical Evangelist on Microsoft Azure and DevOps, will discuss how to accomplish this and more utilizing technologies such as Microsoft Azure, Visual Studio online, and Application Insights in this demo-heavy session.
Nov. 27, 2014 09:45 AM EST Reads: 860
DevOps is all about agility. However, you don't want to be on a high-speed bus to nowhere. The right DevOps approach controls velocity with a tight feedback loop that not only consists of operational data but also incorporates business context. With a business context in the decision making, the right business priorities are incorporated, which results in a higher value creation. In his session at DevOps Summit, Todd Rader, Solutions Architect at AppDynamics, discussed key monitoring techniques...
Nov. 27, 2014 09:30 AM EST Reads: 833
Some developers believe that monitoring is a function of the operations team. Some operations teams firmly believe that monitoring the systems they maintain is sufficient to run the business successfully. Most of them are wrong. The complexity of today's applications have gone far and beyond the capabilities of "traditional" system-level monitoring tools and approaches and requires much broader knowledge of business and applications as a whole. The goal of DevOps is to connect all aspects of app...
Nov. 27, 2014 09:30 AM EST Reads: 382
SYS-CON Media announced that Centrify, a provider of unified identity management across cloud, mobile and data center environments that delivers single sign-on (SSO) for users and a simplified identity infrastructure for IT, has launched an ad campaign on Cloud Computing Journal. The ads focus on security: how an organization can successfully control privilege for all of the organization’s identities to mitigate identity-related risk without slowing down the business, and how Centrify provides ...
Nov. 27, 2014 09:15 AM EST Reads: 1,235
15th Cloud Expo, which took place Nov. 4-6, 2014, at the Santa Clara Convention Center in Santa Clara, CA, expanded the conference content of @ThingsExpo, Big Data Expo, and DevOps Summit to include two developer events. IBM held a Bluemix Developer Playground on November 5 and ElasticBox held a Hackathon on November 6. Both events took place on the expo floor. The Bluemix Developer Playground, for developers of all levels, highlighted the ease of use of Bluemix, its services and functionalit...
Nov. 27, 2014 09:00 AM EST Reads: 593
"We help companies that are using a lot of Software as a Service. We help companies manage and gain visibility into what people are using inside the company and decide to secure them or use standards to lock down or to embrace the adoption of SaaS inside the company," explained Scott Kriz, Co-founder and CEO of Bitium, in this SYS-CON.tv interview at 15th Cloud Expo, held Nov 4–6, 2014, at the Santa Clara Convention Center in Santa Clara, CA.
Nov. 27, 2014 08:45 AM EST Reads: 1,160
"SAP had made a big transition into the cloud as we believe it has significant value for our customers, drives innovation and is easy to consume. When you look at the SAP portfolio, SAP HANA is the underlying platform and it powers all of our platforms and all of our analytics," explained Thorsten Leiduck, VP ISVs & Digital Commerce at SAP, in this SYS-CON.tv interview at 15th Cloud Expo, held Nov 4-6, 2014, at the Santa Clara Convention Center in Santa Clara, CA.
Nov. 27, 2014 08:15 AM EST Reads: 1,214
SAP is delivering break-through innovation combined with fantastic user experience powered by the market-leading in-memory technology, SAP HANA. In his General Session at 15th Cloud Expo, Thorsten Leiduck, VP ISVs & Digital Commerce, SAP, discussed how SAP and partners provide cloud and hybrid cloud solutions as well as real-time Big Data offerings that help companies of all sizes and industries run better. SAP launched an application challenge to award the most innovative SAP HANA and SAP HANA...
Nov. 27, 2014 08:00 AM EST Reads: 1,180
One of the biggest challenges when developing connected devices is identifying user value and delivering it through successful user experiences. In his session at Internet of @ThingsExpo, Mike Kuniavsky, Principal Scientist, Innovation Services at PARC, described an IoT-specific approach to user experience design that combines approaches from interaction design, industrial design and service design to create experiences that go beyond simple connected gadgets to create lasting, multi-device exp...
Nov. 27, 2014 08:00 AM EST Reads: 1,101
Enthusiasm for the Internet of Things has reached an all-time high. In 2013 alone, venture capitalists spent more than $1 billion dollars investing in the IoT space. With "smart" appliances and devices, IoT covers wearable smart devices, cloud services to hardware companies. Nest, a Google company, detects temperatures inside homes and automatically adjusts it by tracking its user's habit. These technologies are quickly developing and with it come challenges such as bridging infrastructure gaps,...
Nov. 27, 2014 07:45 AM EST Reads: 1,416
"Cloud consumption is something we envision at Solgenia. That is trying to let the cloud spread to the user as a consumption, as utility computing. We want to allow the people to just pay for what they use, not a subscription model," explained Ermanno Bonifazi, CEO & Founder of Solgenia, in this SYS-CON.tv interview at Cloud Expo, held Nov 4–6, 2014, at the Santa Clara Convention Center in Santa Clara, CA.
Nov. 27, 2014 07:15 AM EST Reads: 1,034
The Domain Name Service (DNS) is one of the most important components in networking infrastructure, enabling users and services to access applications by translating URLs (names) into IP addresses (numbers). Because every icon and URL and all embedded content on a website requires a DNS lookup loading complex sites necessitates hundreds of DNS queries. In addition, as more internet-enabled ‘Things' get connected, people will rely on DNS to name and find their fridges, toasters and toilets. Acco...
Nov. 27, 2014 07:00 AM EST Reads: 1,387
"For the past 4 years we have been working mainly to export. For the last 3 or 4 years the main market was Russia. In the past year we have been working to expand our footprint in Europe and the United States," explained Andris Gailitis, CEO of DEAC, in this SYS-CON.tv interview at Cloud Expo, held Nov 4–6, 2014, at the Santa Clara Convention Center in Santa Clara, CA.
Nov. 27, 2014 06:45 AM EST Reads: 1,182