|By Business Wire||
|April 29, 2014 12:03 PM EDT||
Bina Technologies today announced the early release of the Bina Annotation Platform, the newest addition to Bina’s highly scalable and accurate genomic analysis product suite. With this addition, Bina allows users to perform secondary analysis (alignment, variant calling) as well as annotation and filtering on their NGS datasets in an integrated, easy-to-use platform with unprecedented speed and scalability.
The Bina Annotation Platform is the fastest, most scalable annotation solution available on the market, empowering scientists to access more than 130 annotation features and search, filter, and annotate their variant files in a fraction of a second. Users can define and save custom and multi-level filters using any combination of important associations and functional databases available on the platform.
Typical NGS whole genome studies yield between 4-5 million variants. Because of the complexity and sheer amount of data, assigning biological meaning and extracting the relevant variants remains one of the primary challenges that biologists and clinical researchers face. Whereas many current annotation tools can’t process an entire whole human genome, the Bina Annotation Module can easily and quickly annotate complex whole genome data sets.
“The Bina Annotation platform provides a great way to comprehensively annotate sequence variants,” said Dr. Ekta Khurana, Yale University. “The user-interface is very intuitive and the process is very fast, allowing more downstream analyses in a fraction of the time required with other approaches.” Dr. Khurana, a research scientist in the Program in Computational Biology and Bioinformatics, is the primary author of a recent publication in Science on annotating human gene variants for cancer genomics applications.
Users can upload their NGS data analysis results or push them directly from Bina’s secondary analysis appliances to the cloud-based Bina Annotation Platform. The Platform then quickly provides current information about relevant variants using databases that are in active use by the scientific community, including HGMD, PGMD, ClinVar, COSMIC, dbNSFP, TRANSFAC, 1000 Genomes, and more. Once the annotation is complete, researchers can interact with their data in real-time, through filtering of all identified variants according to user selected annotation and data quality criteria. All this takes place in an intuitive and easy-to-use interface designed specifically for the clinical researcher.
“Bina’s Annotation Platform provides comprehensive annotation to NGS data with the most relevant scientific and clinical content. Its sub-second query response for WGS and WES (whole genome and whole exome) is unprecedented, definitely facilitating genome interpretation,” added Dr. Shashikant Kulkarni, Associate Professor, Pathology and Immunology and the Head of Clinical Genomics, Genomics and Pathology Services at Washington University School of Medicine
“Prior to Bina’s Annotation Platform, researchers had to wait days, if not weeks, to perform partial analysis on a whole human genome,” said Narges Bani Asadi, CEO of Bina Technologies. “Today, clinical researchers have the ability to bring meaning to their entire NGS data sets in under 60 minutes. Faster, smarter annotation takes us one step closer to our goal of bringing personalized medicine tools to academic and clinical researchers everywhere.”
The Bina Technologies team will be presenting the Bina Annotation Platform to the public this week at the Bio-IT World Expo from April 29th - May 1 in Boston, MA. They will be exhibiting at booth #260, and will present on April 29th at the Vendor Showcase.
To learn more about Bina’s Annotation Platform, please visit: http://binatechnologies.com.
About Bina Technologies
Bina Technologies is defining the standards of high performance genomic analysis. Bina’s integrated, scalable, and comprehensive analysis platform empowers clinical and academic researchers to gain insight from their genomics data sets. Bina’s products dramatically decrease the complexity, time, and cost of the analysis, accelerating the science of personalized medicine.
Bina is an interdisciplinary team of engineers, computer scientists, and genomics scientists, revolutionizing human health and genomics research.
To learn more, visit: http://binatechnologies.com.
SYS-CON Events announced today the DevOps Foundation Certification Course, being held June ?, 2015, in conjunction with DevOps Summit and 16th Cloud Expo at the Javits Center in New York City, NY. This sixteen (16) hour course provides an introduction to DevOps – the cultural and professional movement that stresses communication, collaboration, integration and automation in order to improve the flow of work between software developers and IT operations professionals. Improved workflows will res...
May. 3, 2015 12:30 PM EDT Reads: 3,184
As cloud gives an opportunity to businesses to buy services externally – how is cloud impacting your customers? In his General Session at 15th Cloud Expo, Fabio Gori, Director of Worldwide Cloud Marketing at Cisco, provided answers to big questions: Do you see hybrid cloud as where the world is going? What benefits does it bring? And how does Cisco connect all of these clouds? He also discussed Intercloud and Cisco’s investment on it.
May. 3, 2015 12:00 PM EDT Reads: 4,960
SYS-CON Events announced today that B2Cloud, a provider of enterprise resource planning software, will exhibit at SYS-CON's 16th International Cloud Expo®, which will take place on June 9-11, 2015, at the Javits Center in New York City, NY. B2cloud develops the software you need. They have the ideal tools to help you work with your clients. B2Cloud’s main solutions include AGIS – ERP, CLOHC, AGIS – Invoice, and IZUM
May. 3, 2015 12:00 PM EDT Reads: 4,325
Containers and microservices have become topics of intense interest throughout the cloud developer and enterprise IT communities. Accordingly, attendees at the upcoming 16th Cloud Expo at the Javits Center in New York June 9-11 will find fresh new content in a new track called PaaS | Containers & Microservices Containers are not being considered for the first time by the cloud community, but a current era of re-consideration has pushed them to the top of the cloud agenda. With the launch ...
May. 3, 2015 12:00 PM EDT Reads: 3,660
A new definition of Big Data & the practical applications of the defined components & associated technical architecture models This presentation introduces a new definition of Big Data, along with the practical applications of the defined components and associated technical architecture models. In his session at Big Data Expo, Tony Shan will start with looking into the concept of Big Data and tracing back the first definition by Doug Laney, and then he will dive deep into the description of 3V...
May. 3, 2015 12:00 PM EDT Reads: 905
SYS-CON Events announced today that MangoApps will exhibit at SYS-CON's 16th International Cloud Expo®, which will take place on June 9-11, 2015, at the Javits Center in New York City, NY., and the 17th International Cloud Expo®, which will take place on November 3–5, 2015, at the Santa Clara Convention Center in Santa Clara, CA. MangoApps provides private all-in-one social intranets allowing workers to securely collaborate from anywhere in the world and from any device. Social, mobile, and eas...
May. 3, 2015 11:00 AM EDT Reads: 4,256
There is no doubt that Big Data is here and getting bigger every day. Building a Big Data infrastructure today is no easy task. There are an enormous number of choices for database engines and technologies. To make things even more challenging, requirements are getting more sophisticated, and the standard paradigm of supporting historical analytics queries is often just one facet of what is needed. As Big Data growth continues, organizations are demanding real-time access to data, allowing immed...
May. 3, 2015 11:00 AM EDT Reads: 5,491
The world's leading Cloud event, Cloud Expo has launched Microservices Journal on the SYS-CON.com portal, featuring over 19,000 original articles, news stories, features, and blog entries. DevOps Journal is focused on this critical enterprise IT topic in the world of cloud computing. Microservices Journal offers top articles, news stories, and blog posts from the world's well-known experts and guarantees better exposure for its authors than any other publication. Follow new article posts on T...
May. 3, 2015 11:00 AM EDT Reads: 2,761
WebRTC defines no default signaling protocol, causing fragmentation between WebRTC silos. SIP and XMPP provide possibilities, but come with considerable complexity and are not designed for use in a web environment. In his session at @ThingsExpo, Matthew Hodgson, technical co-founder of the Matrix.org, discussed how Matrix is a new non-profit Open Source Project that defines both a new HTTP-based standard for VoIP & IM signaling and provides reference implementations.
May. 3, 2015 10:45 AM EDT Reads: 4,161
The security devil is always in the details of the attack: the ones you've endured, the ones you prepare yourself to fend off, and the ones that, you fear, will catch you completely unaware and defenseless. The Internet of Things (IoT) is nothing if not an endless proliferation of details. It's the vision of a world in which continuous Internet connectivity and addressability is embedded into a growing range of human artifacts, into the natural world, and even into our smartphones, appliances, a...
May. 3, 2015 10:30 AM EDT Reads: 5,173
There are 182 billion emails sent every day, generating a lot of data about how recipients and ISPs respond. Many marketers take a more-is-better approach to stats, preferring to have the ability to slice and dice their email lists based numerous arbitrary stats. However, fundamentally what really matters is whether or not sending an email to a particular recipient will generate value. Data Scientists can design high-level insights such as engagement prediction models and content clusters that a...
May. 3, 2015 10:15 AM EDT Reads: 4,243
Database apps on mobile devices shouldn't stop working when there's limited or no network connectivity. In his session at 16th Cloud Expo, Bradley Holt, a Developer Advocate for IBM Cloudant, will discuss how to bring data stored in a cloud database to the edge of the network (and back again), whenever an Internet connection is available. He will demonstrate techniques for replicating cloud databases with mobile devices in order to build offline-enabled mobile apps that can provide a better,...
May. 3, 2015 10:00 AM EDT Reads: 891
The Internet of Things is not new. Historically, smart businesses have used its basic concept of leveraging data to drive better decision making and have capitalized on those insights to realize additional revenue opportunities. So, what has changed to make the Internet of Things one of the hottest topics in tech? In his session at @ThingsExpo, Chris Gray, Director, Embedded and Internet of Things, discussed the underlying factors that are driving the economics of intelligent systems. Discover ...
May. 3, 2015 10:00 AM EDT Reads: 5,355
SYS-CON Events announced today the IoT Bootcamp – Jumpstart Your IoT Strategy, being held June 9–10, 2015, in conjunction with 16th Cloud Expo and Internet of @ThingsExpo at the Javits Center in New York City. This is your chance to jumpstart your IoT strategy. Combined with real-world scenarios and use cases, the IoT Bootcamp is not just based on presentations but includes hands-on demos and walkthroughs. We will introduce you to a variety of Do-It-Yourself IoT platforms including Arduino, Ras...
May. 3, 2015 10:00 AM EDT Reads: 3,786
SYS-CON Media announced today that @WebRTCSummit Blog, the largest WebRTC resource in the world, has been launched. @WebRTCSummit Blog offers top articles, news stories, and blog posts from the world's well-known experts and guarantees better exposure for its authors than any other publication. @WebRTCSummit Blog can be bookmarked ▸ Here @WebRTCSummit conference site can be bookmarked ▸ Here
May. 3, 2015 09:45 AM EDT Reads: 3,206