MECHELEN, BELGIUM -- (MARKET WIRE) -- 04/10/07 --

Mechelen, Belgium; 10 April 2007 - Galapagos NV (Euronext & LSE: GLPG) announced today that it has issued 628,058 new shares in relation to the Inpharmatica acquisition and a warrant exercise.

On 6 December 2006, Galapagos announced the acquisition of UK- based Inpharmatica Ltd. Under the acquisition agreement, the shareholders of Inpharmatica have contributed their C Preference shares to the capital of Galapagos, in exchange for a maximum of 2,165,532 newly to be issued Galapagos shares. A first tranche of 623,582 Galapagos shares was issued to former Inpharmatica shareholders in December 2006 as consideration for the contribution of their shares. On 6 April 2007, a second tranche of 613,270 new Galapagos shares was issued and allocated to the former Inpharmatica shareholders as further consideration. A commercial milestone relating to Inpharmatica's business, that was anticipated for Q1 2007 and that would have significantly increased the number of Galapagos shares to be issued in further consideration, was not achieved by Inpharmatica at the agreed upon due date; hence, no Galapagos shares need to be issued in connection with this milestone, reducing the total purchase price of Inpharmatica with 815,302 Galapagos shares. A third tranche of a maximum of 113,378 Galapagos shares is expected to be issued on 7 May 2007 as final part of the consideration for the acquisition of Inpharmatica. The newly issued shares are subject to a lock up agreement ending 10 May 2007.

On 4 April 2007, a total of 14,788 new shares were issued as a result of the exercise of warrants by (ex-) employees of Galapagos and its Dutch affiliate, which were granted under the Warrant Plan 2002 Belgium and the Warrant Plan 2002 The Netherlands.

As a result of both share issues, the number of Galapagos' shares outstanding as of 6 April 2007 is 20,479,388 shares, representing a share capital of EUR 111,256,659.15. All newly issued shares rank pari passu with Galapagos' existing shares.

About Galapagos

Galapagos (Euronext Brussels, GLPG; Euronext Amsterdam, GLPGA; London AiM: GLPG) is a drug discovery company with clinical and pre- clinical programs in bone and joint diseases, cachexia, and menopausal hot flashes. Its division BioFocus DPI offers a full suite of target-to-drug discovery products and services to pharmaceutical and biotech companies, encompassing target discovery and validation, screening and drug discovery through to delivery of pre- clinical candidates. BioFocus DPI also provides adenoviral reagents for rapid identification and validation of novel drug targets, compound libraries for drug screening as well as chemogenomics and ADMET[1] database products to select targets and compounds. Galapagos currently employs 450 people and operates facilities in eight countries, with global headquarters in Mechelen, Belgium. More information about Galapagos and BioFocus DPI can be found at www.glpg.com.

CONTACT

Galapagos NV
Onno van de Stolpe, CEO
Tel: +31 6 2909 8028
ir@glpg.com

This release may contain forward-looking statements, including, without limitation, statements containing the words "believes," "anticipates," "expects," "intends," "plans," "seeks," "estimates," "may," "will," "could," "stands to," and "continues," as well as similar expressions. Such forward-looking statements may involve known and unknown risks, uncertainties and other factors which might cause the actual results, financial condition, performance or achievements of Galapagos, or industry results, to be materially different from any historic or future results, financial conditions, performance or achievements expressed or implied by such forward-looking statements. Given these uncertainties, the reader is advised not to place any undue reliance on such forward- looking statements. These forward-looking statements speak only as of the date of publication of this document. Galapagos expressly disclaims any obligation to update any such forward-looking statements in this document to reflect any change in its expectations with regard thereto or any change in events, conditions or circumstances on which any such statement is based, unless required by law or regulation.

[1] ADMET is the acronym for Absorption, Distribution, Metabolism, Excretion, and Toxicity: Meeting parameters against these five criteria is critical to the success of a pharmaceutical compound as a drug.

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